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'Supernatural' season 9 spoilers: The effects of the Mark of Cain on Dean

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Misha Collins makes his directorial debut on "Supernatural" with episode 917, "Mother's Little Helper," for which the CW released an official description on Wednesday, March 5.

If you've been wondering what happened to the Mark of Cain on Dean (Jensen Ackles) on "Supernatural," this is the episode for you. In "First Born," Dean and Crowley (Mark Sheppard) met Cain, who gave Dean the Mark. Meanwhile, Crowley's supposed to be tracking down The First Blade to kill Abaddon, but as the "Blade Runners" promo has revealed, he's a bit too busy with his addiction and the Winchesters are going to have to get him back on track.

However, it sounds like Crowley should be doing well enough by this episode to test Dean, but how exactly is he going to test him? And how exactly will Dean be struggling? What are these "after effects" mentioned? We haven't heard anything about the Mark since Dean told Sam about it.

Also, get ready for some flashbacks and familiar faces in this upcoming episode, as Sam (Jared Padalecki) talks to someone who tells him about the Men of Letters in 1958 – specifically, Henry Winchester (Gil McKinney) and Josie Sands (Alaina Huffman).

Here's the CW's official description of "Supernatural" season 9 episode 17, "Mother's Little Helper," written by Adam Glass and directed by Misha Collins:

"MISHA COLLINS MAKES HIS DIRECTING DEBUT — Dean (Jensen Ackles) struggles with the after effects of the Mark of Cain. Meanwhile, Sam (Jared Padalecki) hears about a case where straight-laced people are turning into violent murderers. Sam suspects possession and suggests to Dean that they investigate, but Dean tells him to go without him. While interviewing the local townsfolk, Sam meets an elderly woman named Julia (guest star Jenny O’Hara), who tells him the Men of Letters came to town in 1958. Josie tells Sam the story of a young man named Henry Winchester (guest star Gil McKinney) and his female companion, Josie Sands (guest star Alaina Huffman). While Sam is away, Crowley (Mark Sheppard) tests Dean."

"Supernatural" season 9 airs Tuesdays at 9 p.m. on the CW. "Mother's Little Helper" airs March 25. What are you hoping to see in episode 17?

© Meredith Jacobs 2014

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