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Study: both oral and vaginal Flagyl are effective in treating Bacterial Vaginosis in pregnant women
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According to a report in the most recent edition of the journal, BMC Infectious Diseases, both oral and vaginal metronidazole are effective for treating bacterial vaginosis (BV) in pregnant women.
"Most treatment studies in pregnancy have used oral metronidazole, though vaginal metronidazole is an acceptable option that has shown efficacy against fastidious bacteria," note lead author Dr. Caroline M. Mitchell, of the University of Washington, Seattle.
To examine the effect of each treatment on quantities of fastidious BV-associated bacteria, Dr. Mitchell and colleagues evaluated vaginal fluid samples from a randomized trial of oral versus vaginal metronidazole.
Among 53 women with bacteria detected, the authors report, there were no differences in rates of bacterial persistence between the oral and vaginal treatment groups.
Investigators concluded that both oral and vaginal metronidazole therapy in pregnant women results in a significant decrease in concentrations of most BV-associated anaerobic bacteria, with a few exceptions that showed little decrease using the vaginal therapy. These data suggest that the route of antibiotic administration has a minor impact on bacterial eradication in pregnant women with BV.
The Centers of Disease Control and Prevention (CDC) say that treatment is especially important for pregnant women. All pregnant women who have ever had a premature delivery or low birth weight baby should be considered for a BV examination, regardless of symptoms, and should be treated if they have BV. All pregnant women who have symptoms of BV should be checked and treated.
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