
Roy Schwank, MD, dedicated much of his research career to multiple sclerosis (MS) and how multiple sclerosis exacerbation is linked to diet.
Schwank, who began his work in Norway and later continued his work at the Oregon Medical School, published the results of his best-known trial in 1990 in the Lancet. Schwank followed 144 patients recruited from the Montreal Neurological Institute for 34 years. He advised these patients to follow a low saturated fat diet. Knowing that some would adhere to the diet and some would not, he grouped them into good dieters (those who ate < 20 grams of saturated fat/day) and poor dieters (those who ate > 20 grams of saturated fat/day).
As the study progressed, Schwank found that the good dieters experienced slower progression of the disease. Most of the poor dieters, according to Schwank, "became severely disabled and had a high death rate."
Based on this research, high saturated fat diets have a strong link with multiple sclerosis exacerbation. In the discussion part of the Lancet article, the authors write that other research has shown that multiple sclerosis patients who eat 10-15 grams of saturated fat per day or less fare even better.
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Source: Swank RL, Dugan BB. Effect of low saturated fat diet in early and late cases of multiple sclerosis. Lancet.1990;336:37-39.