In a game where they were probably still a bit jet-lagged from the plane ride from London, the Bulls (2-1) fell to the Milwaukee Bucks (1-2) 98-86, Saturday night in Green Bay Wis.
The Bucks entered the game having given up 117 points to the Timberwolves and 113 to the Pistons and it was obvious from the start, they had the fresher legs.
The Bulls committed 27 turnovers and seemed a step slow and a little sloppy on the offensive end.
The Bucks were led by Hakim Warrick's 13 points and 8 rebounds.
James Johnson led the team with 14 points, 7 rebounds, but also provided 6 of the teams turnovers. Kirk Hinrich and Jannero Pargo added 13 apiece.
Tyrus Thomas (concussion) and Derrick Rose (right ankle) sat out their second consecutive game.
The Bulls return home, where they will play the Buck again on Tuesday.