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WHO investigates H1N1 mutations for changes in virus - Swine flu mutations increasing worldwide

November 27, 10:48 AMHealth Technology ExaminerVictoria Nicks
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Worldwide Spread of H1N1 as of November 20
Courtesy Centers for Disease Control and Prevention

H1N1 mutations have been reported in countries around the world, most notably in China, Ukraine, Norway, Japan, Wales, and the United States. One reported mutation involves the resistance to antiviral drugs. Another mutation, found in the Ukraine flu, as well as the outbreaks in China, Norway, and the United States, results in hemorrhaging or bleeding in the lungs. According to Keiji Fakuda, the World Health Organization (WHO)'s special adviser on pandemic influenza, the WHO is now trying to determine if the symptoms associated with H1N1 mutation are more likely to be severe or mild.

Swine flu mutation causes antiviral resistance

One swine flu mutation that has been found in various isolated individuals worldwide, as well as in clusters in the U.S. and Wales, results in a resistance to Tamiflu. Tamiflu is an antiviral medication used to reduce the severity of viral infections. The mutated strain of H1N1 that is resistant to Tamiflu still responds to Relenza.

Lung Hemorrhage from H1N1 mutation

A mutation involving the receptor binding domain of the H1N1 virus has been identified in cases in China, the Ukraine, Norway, and the United States. In these cases, the swine flu virus infects deep in the lungs, seriously affecting the respiratory system.

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