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Robert Scheinman joined the University of Colorado faculty in 1995. His laboratory has published on Diabetes, Arthritis, and Cancer. Robert teaches topics ranging from diabetes to chronic inflammatory disease to molecular biology. Email him: robscheinman@gmail.com

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Showing: Fundamental Concepts articles

Diabetes 101: What are incretin based therapies?

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Treatments for diabetes have one goal: to get sugar out of the blood and into tissues. Insulin plays a critical...
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Scientists move one step closer on the path to building a pancreas

The cure for diabetes will involve replacing lost pancreatic function and what better source than your own stem cells. Getting from the stem cell to...
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Diabetes 101: What do transcription factors have to do with a cure for type 1 diabetes? (part 2)

In the previous article we defined a transcription factor. Here we will use them to build organs. Going back to the pancreatic beta cell, all of the...
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Diabetes 101: What do transcription factors have to do with a cure for type 1 diabetes?

To cure type 1 diabetes we need to do 2 things. Firstly, since the patient has no more pancreatic beta cells to produce insulin we need to make new...
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Diabetes 101: thymic selection part 2

To recap from yesterday’s column: when a thymocyte finds a piece of self presented as an antigen, and if it responds…reluctantly, then it...
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Diabetes 101: thymic selection part 1

Type I diabetes occurs because of things which happen at the beginning; the time during which the fetal immune system begins to take its form. To...
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Mental control of blood sugar levels is a reality for diabetes patients

It is extraordinarily clear that the mind plays some role in the amount of sugar in your blood stream. The important question is…how much?...
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Diabetes 101: MHC presentation and MHC restriction part 2

To start from the beginning click here. There are a great many different proteins in this world and so there are an astronomical number of different...
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Diabetes 101: MHC presentation and MHC restriction

Some of the risk of developing Type I diabetes is genetic. It has been estimated that approximately 50% of this genetic risk is contributed by a...
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Understanding diabetes: the T cell receptor (part II)

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To start at the beginning of this article click here.For those of you who play the lottery, think about how many numbers you pick and the chances of...
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