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Insulin resistance is the hallmark of prediabetes. The disease has not yet set in because the pancreas can compensate for this by increasing the...
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Find out more about Robert: Robert Scheinman joined the University of Colorado faculty in 1995. His laboratory has published on Diabetes, Arthritis, and Cancer. Robert teaches topics ranging from diabetes to chronic inflammatory disease to molecular biology. Email him: robscheinman@gmail.com |
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Diabetes Examiner's Articles
Showing: Disease Mechanism articles
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Exercise improves insulin resistance. We’ve known this for some time. Somehow, exercise strengthens the...
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Prediabetes is almost always associated with a decreased ability to respond to insulin: a state we call insulin...
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Type 1 diabetes is an autoimmune disease. If a doctor takes a biopsy of pancreatic tissue from a child who has been...
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We have known for quite some time that obesity and type 2 diabetes is associated with a state of chronic inflammation. One of the ways we study this...
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Carnitine has been of interest to diabetes doctors and researchers for some time. Indeed a search of the National Library of Medicine using the terms...
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We are focused these days on decreasing our environmental carbon footprint as a means to stabilize our planetary ecosystem. Similarly, our cells also...
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Over a decade before the diagnosis of type 2 diabetes, changes in blood sugar and insulin resistance can be detected in at risk individuals.This week...
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To start at the beginning of this article click here.For those of you who play the lottery, think about how many numbers you pick and the chances of...
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Type I diabetes is an autoimmune disease. To understand it, one must understand how the immune system “sees” the world. Military analogies...
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- Depletion of cytosolic phospholipase A2 in bone marrow-derived macrophages protects against lung cancer progression and metastasis.
- Unmasking of a protective tumor necrosis factor receptor I-mediated signal in the collagen-induced arthritis model.
- Loss of a gimap/ian gene leads to activation of NF-kappaB through a MAPK-dependent pathway.
- AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix.
- Partial activation precedes apoptotic death in T cells harboring an IAN gene mutation.
- Increased NF-kappa B activity in B cells and bone marrow-derived dendritic cells from NOD mice.
- The identification of a novel T cell activation state controlled by a diabetogenic gene.
