The grille and badge on the 2010 Lexus RX 450h differ from the RX 350, having a "Lexus hybrid blue background.
- The grille and badge on the 2010 Lexus RX 450h differ from the RX 350, having a "Lexus hybrid blue background.
- The Lexus RX 450h has a sculpted body with deep contours than its predecessor, the Lexus RX 400h.
- The Lexus RX 450h has its own front bumper contours, differing from the gas-engined RX 350.
- The contours on the RX 450h include deeper shoulders.
- The 3.5-liter gasoline engine peaks out of the shrouding that reduces any stray engine noises.
- The RX 450h replaces the tachometer from a gas engined RX with a gauge that helps drivers monitor energy use, from blue for recharge, green for economical operation and white for max power output.
- The 2010 RX models facilitate folding the back seat to increase cargo capacity with a lever on either side of the compartment rather than on the seatbacks, which require walking from one side to the other to drop the seats.
- The steeply sloped rear window reduces load capacity, particularly for large bulky items. The rear spoiler is now standard and hides the top-mounted wiper.
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