The success of Frankenstein (1931), not only brought stardom to Boris Karloff, but also brought prominence to its director James Whale.
One of Whale’s following films was this adaptation of the 1897 H.G. Wells novel, about scientist Jack Griffin (played by Claude Rains, after original choice Karloff backed out), who develops a serum which renders him invisible. In his search for a way to become visible again, however, Griffin slowly loses his mind as the potential of what he can do gets the better of him, to the horror of his love Flora (Gloria Stuart).
Whale brings the same wonderful balance of humor and horror he would later bring to The Bride of Frankenstein (1935). The SFX remain eye-popping even today, and Rains is fabulous, scaring us with only his great voice (there is only a brief moment in the movie when the actor is seen).
Naturally, there were follow-ups to this film, none of which hold a candle to the original, although, in fairness, they were better than Memoirs of an Invisible Man (1992) and Hollow Man (2000).
Rains would go onto a great career with films including The Wolf Man (1941), Casablanca (1942) and Lawrence of Arabia (1962). Stuart, likewise, would gain a new generations of fans decades later with her Oscar-nominated work in Titanic (1997).