In a nutshell, the book is about a girl who befriends a squirrel who has superpowers after an encounter with a vacuum cleaner. The squirrel also helps Flora, her parents, and a neighborhood kid overcome family problems.
The main reason why I enjoyed this book was the humor. DiCamillo was extremely creative when plotting out events and developing characters. Who would have thought of having a squirrel with superpowers? A crazy mom who writes romance novels and has a lamp that looks like Little Bo Peep? A boy in the neighborhood who thinks he is blind? DiCamillo did, and somehow she managed to blend it all together to make a wonderful story. The artwork by K.G. Campbell made the book even more wonderful with the hilarious comic strips depicting moments of intensity such as squirrel vs. vacuum, squirrel vs. cat, and squirrel vs. waitress's hair.
Another thing that I liked about this book was that DiCamillo managed to embed some serious moments and issues into a book that is disguised as only humorous. For example, DiCamillo portrays the issues of divorce as seen through the eyes of a child with complete honesty and sincerity. She also writes about grief, and ungrateful spouses.
There isn't a thing that I didn't like about this book. I caught myself laughing out loud while reading many parts of Flora and Ulysses, and I strongly recommend this book to everyone!