SAN FRANCISCO (Map) - SAN FRANCISCO, May 15 /PRNewswire-FirstCall/ -- Medivation, Inc. (Nasdaq: MDVN) today announced that data from an ongoing Phase 1-2 clinical trial of its novel androgen receptor antagonist, MDV3100, will be presented in an oral presentation at the 44th American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

    Session title: New Targeted Strategies for Patients with Prostate Cancer
    Session date and time: Monday, June 2 at 11:30 a.m. Central Time
    Abstract title: "Phase 1-2 Study of MDV3100 in Patients with Progressive
    Castration-Resistant Prostate Cancer (CRPC)" (Abstract #5006)
    To be presented by: Howard Scher, M.D., chief of the Genitourinary
    Oncology Service and the D. Wayne Calloway Chair in Urologic Oncology at
    Memorial Sloan-Kettering Cancer Center in New York, at approximately 12:15
    p.m. Central Time
    Location: W375e

Dr. Scher's presentation will include data appearing in the abstract posted today on the ASCO website, as well as additional study data not reflected in the abstract.

Medivation's ongoing Phase 1-2 trial of MDV3100 is an open-label dose-escalation study enrolling prostate cancer patients who have failed standard hormonal therapies. The study endpoints include safety, tolerability, pharmacokinetics, effects on serum PSA levels and disease progression. Medivation expects to complete the study and report final top-line results in 2008.

About Prostate Cancer

Prostate cancer is the most common type of cancer, other than skin cancer, and the second leading cause of cancer death in American men. More than 1 million men in the United States have prostate cancer. An estimated 186,320 new cases are expected to be diagnosed in 2008, and approximately 28,660 men are expected to die this year from the disease(1). Patients with castration-resistant (also known as hormone-refractory) prostate cancer have few treatment options and a poor prognosis.

About Medivation

Medivation, Inc. is a biopharmaceutical company focused on the rapid development of novel small molecule drugs to treat serious diseases of the central nervous system and cancers for which there are limited treatment options. Medivation aims to revolutionize the treatment of these diseases and offer hope to critically ill patients and their caregivers. The Company's current clinical development program includes a pivotal and confirmatory Phase 3 trial of Dimebon(TM) in Alzheimer's disease, a Phase 2 clinical trial of Dimebon in patients with mild-to-moderate Huntington's disease, and a Phase 1-2 clinical trial of MDV3100 in patients with castration-resistant (also known as hormone-refractory) prostate cancer. For more information, please visit us at http://www.medivation.com.

This press release contains forward-looking statements, including statements regarding anticipated clinical and regulatory milestones, which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements involve risks and uncertainties that could cause actual results to differ significantly from those projected. You are cautioned not to place undue reliance on the forward-looking statements, which speak only as of the date of this release. None of the Company's product candidates has been approved for sale, significant additional animal and human testing is required in order to seek marketing approval for any of its product candidates, and Medivation cannot assure you that marketing approval can be obtained for any of its product candidates. Furthermore, as is typically the case at this stage of the regulatory review process, the FDA has not yet performed an in-depth review of Medivation's preclinical and clinical data, so its views remain subject to change. Medivation's filings with the Securities and Exchange Commission, including its Annual Report on Form 10-KSB for the year ended December 31, 2007 and its Quarterly Report on Form 10-Q for the quarter ended March 31, 2008, include information about additional factors that could affect the Company's financial and operating results.

(1) American Cancer Society Web Site; Overview: Prostate Cancer

(http://www.cancer.org/docroot/CRI/CRI_2_1x.asp?dt=36)