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- National Intelligence Director Mike McConnell says the terrorist group U.S. intelligence believes carried out last week's attack in Mumbai is the same one that attacked Mumbai trains in 2006.
Ga. Senate runoff could decide balance of power- Georgia's seemingly endless U.S. Senate campaign drew to a finish on Tuesday as polls closed on the hotly-contested race that will sway the balance of power in Washington.
Gates: Military looks to accelerate Iraq pullout- Defense Secretary Robert Gates signaled a willingness Tuesday to forge ahead with two key priorities for the incoming Obama administration: accelerating the U.S. withdrawal from Iraq and shutting down the Guantanamo Bay detention center.
- The divorce rate among soldiers and Marines increased last year as military marriages suffered continuing stress from America's two ongoing wars. There were an estimated 10,200 failed marriages in the active duty Army and 3,077 among Marines, according to figures obtained by the Associated Press for the budget year ended Sept. 30.
Auditors fault Treasury oversight of bailout funds- The government must toughen its monitoring of the $700 billion financial bailout to ensure that banking institutions limit their top executives' pay and comply with other restrictions, federal auditors said Tuesday in the first comprehensive review of the rescue package.
Chained teen shows up at Calif. gym; 2 arrested- A Girl Scout leader and her husband were arrested after an emaciated, terrified and nearly naked 17-year-old showed up at a gym with a chain locked to his ankle, saying he had just fled his captors, authorities said Tuesday.
Nixon records show aides dishing dirt on critics- In Richard Nixon's time, all the president's men fretted about threats on every front: disquiet out on the streets, disloyalty inside the administration and trouble from political opponents who had to be discredited at any cost.
Coleman pleads no contest to disorderly conduct- Gary Coleman has pleaded no contest to a disorderly conduct charge stemming from a September incident at a bowling alley. The 40-year-old former star of "Diff'rent Strokes" was ordered to pay a $100 fine in a Payson court Tuesday. He also pleaded no contest to a reckless driving charge, which will be waived if he doesn't have any other violations within a year.
- A message in a bottle tossed into the ocean off Barnegat Bay has turned up in North Carolina - 39 years later. The note was sealed in a Schaefer beer bottle. It was dated Aug. 17, 1969 and read: "If found notify the North Haledon Fire Co. 2."
NHL suspends Stars' Sean Avery for crude comments- The NHL suspended Dallas Stars forward Sean Avery indefinitely Tuesday for making a crude reference to former girlfriends while talking with reporters.
BiPar Sciences Expands Clinical Program for BSI-201, a Novel DNA Repair Inhibitor, in Brain Cancer
BRISBANE, Calif.
(Map)
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"We believe a multi-drug strategy is the best approach to battling GBM.
There is a significant need for new treatments that can offer GBM patients and
their families additional hope," said
"BSI-201 is a promising agent that has been well tolerated in combination with cytotoxic therapies in patients with solid tumors and potentially addresses a key pathway by which GBM cells resist the effects of existing medications. We are hopeful that BSI-201 will safely potentiate the power of current therapies for GBM and improve survival in this difficult-to-treat cancer," said
"The scientific observations that BSI-201 crosses the blood-brain barrier
and has a mechanistic basis to synergize with the standard treatment of GBM
makes this a promising study," said BiPar Executive Vice President
GBM is an aggressive form of brain cancer that strikes 10,000 patients a
year in
Additional Data to be Presented at Upcoming AACR 2008 Meeting
BiPar will present preclinical data on BSI-201 at the American Association
for Cancer Research (AACR) Annual Meeting in
About BiPar Sciences
BiPar Sciences is a drug development company with a therapeutic focus on novel mechanisms of action in oncology. Our existing platform is based on DNA repair, specifically with poly ADP-ribose polymerase (PARP) inhibitors. BSI-201 is the lead PARP inhibitor program in Phase 2 clinical trials in multiple solid tumor settings.
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