Maria C. S. Inacio, M.S., of the Southern California Permanente Medical Group, San Diego, and colleagues published new research in the Feb. 18, 2013, issue of the journal JAMA Internal Medicine that indicates women have a higher risk of hip implant failure than men.
The results were based on an examination of patients that were enrolled in a total joint replacement registry from April 2001 through December 2010. Total hip replacement, also known as total hip arthroplasty (THA), is more often performed in women than men.
A total of 35,140 THAs with three years of median follow-up were identified in a study population in which 57.5 percent of the patients were women and the average age of the patients was almost 66 years.
"In our analyses of a large THA cohort, including a diverse sample within 46 hospitals, we found that at the median follow up of 3.0 years women have a higher risk of all-cause (HR [hazard ratio], 1.29) and aseptic (HR, 1.32) revision but not septic revision (HR, 1.17)," the authors comment.
“A higher proportion of women received 28-mm femoral heads (28.2 percent vs. 13.1 percent) and had metal on highly cross-linked polyethylene-bearing surfaces (60.6 percent vs. 53.7 percent) than men. Men had a higher proportion of 36-mm or larger heads (55.4 percent vs. 32.8 percent) and metal on metal-bearing surfaces (19.4 percent vs. 9.6 percent). At five-year follow-up, implant survival was 97.4 percent. Device survival for men (97.7 percent) vs. woman (97.1 percent) was significantly different. After adjustments, the hazard ratios for women were 1.29 for all-cause revision, 1.32 for aseptic revision and 1.17 for septic revision, according to the study results.”