60 votes are needed to pass the bill.
Republicans are accusing Democrats of trying to push the bill through in secret nightime darkness while the American people are sound asleep.
This vote is considered by analysts to be key to the success of the Obama administration.
"Ted Kennedy would be disappointed in this bill but he would tell us to vote for it. And I urge my colleagues to support this act." -- Senator Chris Dodd.
Mitch McConnell - Republican - "One state out of 50 gets to expand Medicaid at not tax to itself white the other 49 states food the bill. Do the supporters of the bill know this? What about the rest of the country? With a couple of cheap deals and a rush vote at 1:00 in the morning."
Senator Harry Reid, Democrat Majority Leader -- "For the first time in American history, good health will not depend on high wealth."
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