
A healthy dose of exercise is good medicine, even for lymphoma patients receiving chemotherapy, University of Alberta researchers have found.
The Healthy Exercise for Lymphoma Patients (HELP) trial, a three-year study found that aerobic exercise training produced significant improvements in physical functioning and overall quality of life benefits in patients with lymphoma.
Researchers recruited 122 patients with Hodgkin's and non-Hodgkin's lymphoma, then stratified participants by disease type and treatment status; whether they were undergoing chemotherapy at the time or receiving no treatments. Participants were randomly assigned to an exercise program designed to maximize cardiovascular fitness or to usual care, which did not include an exercise component.
Exercisers trained three times a week for 12 weeks and were encouraged to stay the course with behavioral support techniques that included perks like free parking, a well-equipped gym, flexible exercise schedules, variation in exercises, follow-up phone calls reminders and positive reinforcement by staff.
What were the benefits for exercisers?
Lymphoma patients who received the exercise intervention reported
1. significantly improved physical functioning,
2. significantly improved overall quality of life,
3. less fatigue,
4. increased happiness,
5. less depression and an improvement in lean body mass.
6. cardiovascular fitness in the exercise group improved by over 20 per cent; the group receiving chemotherapy benefited as much as the group that was off treatments
Most importantly...
Vigorous intensity exercise program did not interfere with lymphoma patients' ability to complete their chemotherapy treatments or benefit from the treatments.
Researchers found that 46.4 per cent of patients in the exercise group had a complete response to their treatment (no evidence of disease) compared to only 30.8 per cent in the usual care group.
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