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What ingredient in breast milk protects newborn's delicate intestines?
Scientists at Queen Mary, University of London have discovered that an ingredient in human breast milk protects and repairs the delicate intestines of newborn babies.
The ingredient called pancreatic secretory trypsin inhibitor, or PSTI, is found at its highest levels in colostrum - the milk produced in the first few days after birth.
Why does the newborn’s gut need protection?
The lining of a newborn's gut is particularly vulnerable to damage as it has never been exposed to food or drink. The new study highlights the importance of breastfeeding in the first few days after the birth.
The researchers found small amounts of PSTI in all the samples of breast milk they tested but it was seven times more concentrated in colostrum samples. The ingredient was not found in formula milk.
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007Breasts
Photo courtesy of 007Breasts
The researchers examined the effects of PSTI on human intestinal cells in the lab. When they inflicted damage to the cells they found that PSTI stimulated the cells to move across the damaged area forming a natural protective 'plaster'. They also found that PSTI could prevent further damage by stopping the cells of the intestine from self-destructing. Additional research suggests that PSTI could reduce damage by 75 per cent.
What is PSTI?
PSTI is a molecule which is normally found in the pancreas where it protects the organ from being damaged by the digestive enzymes it produces. Research suggests that it plays a similar protective role in the gut.
Why is this study important?
The researchers say this study is important because it reinforces the benefits of breast feeding, especially in the first few days after birth.
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Copyright, 2009, Carolyn Chambers Clark
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