Skip to main content
  1. Life
  2. Health & Fitness
  3. Holistic Health

Zontivity approved to reduce the danger of heart attacks in high risk patients

See also

Zontivity (vorapaxar), a new class of drugs called protease-activated receptor-1 (PAR-1) antagonist, has now been approved by the FDA to reduce the risk of heart attack, stroke, cardiovascular death, and need for procedures to restore the blood flow to the heart in patients with a previous heart attack or blockages in the arteries to the legs. Available in tablet form, Zontivity is described as “an anti-platelet agent, designed to decrease the tendency of platelets to clump together to form a blood clot. By doing so, the drug lowers the danger of heart attack and stroke.” In fact, a clinical trial involving 25,000 participants showed that when added to other anti-platlet agents such as aspirin and clopidogel, Zontivity also “reduced the rate of a combined endpoint of heart attack, stroke, cardiovascular death, and urgent procedures to improve blood flow to the heart (coronary revascularization).

“Zontivity has been found to reduce risk of heart attack on people who have had them, or who have peripheral arterial disease from 9.5%-7.9% over a 3-year period,” noted Ellis Unger, M.D., director of the Office of Drug Evaluation I in the FDA’s Center for Drug Evaluation and Research.

To learn more readers can contact the FDA information line at 888 Info-FDA.

Advertisement

Life

  • Dan Savage
    Dan Savage cares about LGBT youth, bullying and saving lives
    Today's Buzz
  • Raku
    Teachers and students can use this summer to learn a new skill
    Camera
    15 Photos
  • Beach body
    Fitness: Earn your beach body badge with bootcamp classes
    Camera
    10 Photos
  • Greek wine
    Unwind with these delicious wines: The thrilling wines of Greece
    Camera
    7 Photos
  • Mandy Moore
    Exclusive interview with Celebrity Mandy Moore concerning animal activism
    Camera
    5 Photos
  • Educational family vacations
    Find out how to take an educational family vacation that doesn't break the bank
    Camera
    9 Photos