Published in the journal of endocrine society and science daily, September 19, 2013 online:
- Chemicals pose a threat to human health and to the ecosystems of earth.
Endocrine-disrupting chemicals are substances in our environment, food, and consumer products that interfere with hormonal systems.
‘In this first Scientific Statement of The Endocrine Society, we present the evidence that endocrine disruptors have effects on multiple organs and systems.
- ‘No endocrine system is immune to endocrine disrupting chemical.’
‘Because of the shared properties of the chemicals and the similarities of the receptors and enzymes involved in the synthesis, release, and degradation of hormones, no endocrine system is immune to endocrine disrupting chemical.’
- Transmission and exposure.
‘Effects of endocrine disrupting chemicals may be transmitted to further generations through germ line epigenetic modifications or from continued exposure of offspring to the environmental insult’.
- Exposure to endocrine disrupting agents.
‘There is mounting evidence for disastrous health effects on endocrine systems, including male and female reproduction, breast development and cancer, prostate cancer, neuroendocrinology, thyroid, metabolism and obesity, and cardiovascular endocrinology.’
The group of molecules identified as endocrine disruptors includes synthetic chemicals used as industrial solvents/lubricants and their byproducts.
- Polychlorinated biphenyls or PCBs.
- Polybrominated biphenyls or PBBs.
- Plastics containing bisphenol A or BPA.
- Plasticizers or phthalates.
- Pesticides like methoxychlor, chlorpyrifos, dichlorodiphenyltrichloroethane or DDT.
- Fungicides like vinclozolin.
- Pharmaceutical agents like diethylstilbestrol or DES.
- Natural chemicals found in human and animal food phytoestrogens, including genistein and coumestrol.
‘EDCs are commonly found in food and food containers, plastic products, furniture, toys, carpeting, building materials, and cosmetics. They are often released from the products that contain them and enter the bodies of humans and wildlife through dust or through the food chain’.
Diamanti-Kandarakis E et al 2009 Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement. Endocrine Reviews 30(4):293-342