The WWE follows just 262 people on Twitter, and Punk is no longer one of them.
The decision by the WWE to stop following Punk could mean the promotion is heading towards a nasty divorce with the 35-year-old superstar, or it could mean nothing at all.
In general, it's not really a big deal when someone decides to "unfollow" someone else on Twitter.
However, this story is big news because Punk's contract with the WWE expires this July, and he has been on shaky ground with the promotion in recent weeks.
Punk was apparently so angry Batista won the Royal Rumble that he went home to Chicago, Ill., rather than appearing at Monday Night Raw the next after the 30-man battle.
Punk also did not appear at the WWE Smackdown taping the night after Monday Night Raw.
WWE boss Vince McMahon responded by pulling Punk from all advertising of WWE live events going forward after a lengthy meeting with WWE officials.
One day after the Royal Rumble, Punk tweeted what appeared to be a farewell message to WWE fans.
"Thanks for all the support. Keep being you guys, it's pretty cool," Punk posted on his official Twitter page.
Punk also hinted in a recent interview with MMA Fighting reporter Ariel Helwani that he is tired of the WWE's grueling travel schedule, and that he might be interested in trying his hand at MMA sometime in the near future.
Punk even appeared to be interested in competing on the UFC's long-standing reality show, The Ultimate Fighter.
Fight fans have seen wrestlers leave and come back plenty of times in the past, so there's a good chance WWE Universe hasn't seen the last of Mr. Punk.
Cooler heads will eventually prevail, especially when there's significant amounts of money on the line.