This following a 20 turnover game on Monday in a loss to the Sacramento Kings.
First-time all-star guard Jrue Holiday led the way for the 'Sixers with 21 points including nine in the final quarter.
Former Wizards guard Nick Young carried the load for Philly in the first three quarters scoring 18 points.
Nene led the way for the turnover-prone Wizards with 16 points.
Washington lacked confidence on offense turning down open shots for what often turned into intercepted passes intended for teammates who were covered.
It wasn't more apparent than in the second quarter when Trevor Ariza passed up an open three-pointer with the shot clock running down and kicked it out to Jordan Crawford who was double-teamed leading to a shot-clock violation.
The Wizards were unselfish to a fault.
They really missed the shooting stroke of rookie guard Bradley Beal who missed the game due to a right wrist sprain.
John Wall committed a team-high five turnovers and many of his lost balls came due to dribbling into traffic without anywhere to pass.
The lone bright spot for Washington was a third straight double-double by Emeka Okafor who finished with 15 points and 17 rebounds.
The Wizards travel to Memphis next, on Friday, to play the new-look Grizzlies who traded Rudy Gay to the Toronto Raptors Wednesday evening.
This will be the first game of five straight against teams with records over .500.
The Wizards, who's 15.37 turnovers a game ranked fifth most in the league going into Wednesday night's game, will need to protect the ball better if they want to make sure this two game losing streak doesn't turn into a seven game slump.