The most well known example of a female centric Spielberg film is indeed The Color Purple, which also ended up being his first serious film after a decade of steadily establishing himself as the innovator of summer blockbuster popcorn, alongside contemporary and best friend George Lucas. One of the most interesting aspects of the film that often gets overlooked is how this is actually one of the few times his films had a story based around feminist issues and their commentary, albeit in a fictional context and based on a novel.
A good majority of his other films are either based around main characters who are either young boys or adult males who are ambiguously Jewish. And in both cases, these characters either have daddy issues or are some kind of absentee father themselves. Yet will there ever be a time where Spieberg once again tackles a film with a woman as the main character or a female centric storyline?