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“We’ve won the ethical argument and are winning the scientific argument.”

Transitioning to non-animal, human-based research methods will accelerate science and enhance public safety and health.
Transitioning to non-animal, human-based research methods will accelerate science and enhance public safety and health.
Jeannette Louise Smith

The horrific images, videos, and tales of animal experimentation that occur inside laboratories around the world are undoubtedly and disappointingly true. There is no denial of the unspeakable suffering, torture, and death forced on innocent non-human animals by humans.

“Almost all animals die in animal research,” states John Pippin, M.D., F.A.C.C., Director of Academic Affairs for the Physicians Committee for Responsible Medicine (PCRM). Death is the result of the experiment or death is deliberately inflicted for postmortem examination required by research protocols.

Dr. Pippin, a cardiologist and former animal research practitioner, is a longtime critic of animal experimentation. Since renouncing the validity of animal experimentation, Dr. Pippin has dedicated his life to enhancing the lives of humans and non-human animals by replacing the use of animals in medical and drug research, medical education, and the training of medical professionals, promoting safe and reliable human-based research.

Speaking softly, with a sense of optimistic urgency and positive excitement regarding the shift from invalid and failed animal experimentation practices to more accurate non-animal testing that will benefit both humans and animals, Dr. Pippin wholeheartedly states, “We’ve won the ethical argument and are winning the scientific argument.”

There is no longer a need to debate the moral and ethical arguments regarding animal experimentation because the science of animal experimentation discredits itself.

“Animal research is unnecessary because it doesn’t advance medicine and help people. If it isn’t necessary,” Dr. Pippin says referring to the necessary evil argument, “all that’s left is evil.”

Although all species are related through evolution and comparisons can be made between non-human animals and humans, Dr. Pippin explains, “Specific interspecies differences lead to the increasing failure rates of animal research to reliably inform human medicine.”

“If our closest genetic relative, the chimpanzee, cannot accurately predict human outcomes,” Dr. Pippin elaborates, “then animals less like us certainly cannot predict human outcomes. Even within our own species, situations vary and genes operate differently in individuals.”

Clearly, epidemiological studies, clinical research, in vitro research, in silico (computer-based) techniques, human cell and tissue cultures, stem cell methods, advanced imaging methods, and safe human-based research and studies are the future of scientific research.

Since 2011, the Institute of Medicine (IOM), National Institutes of Health (NIH), Federal Drug Administration (FDA), Environmental Protection Agency (EPA) have begun to acknowledge that biomedical and behavioral animal experimentation has failed to prove the safety and efficacy of drugs, vaccines, and chemicals.

In addition to the convergence of science, medicine, and animal law, Dr. Pippin states, “Funding must be dedicated to the development of better human-based research and drug safety tests.”

Within the current funding framework, the National Institutes of Health (NIH), the largest source of funding for medical research in the world, spends upwards of $14.5 billion U.S. taxpayer funds a year on unnecessary animal experiments.

The National Institutes of Health (NIH) establishes the playing field of what Dr. Pippin calls an “intricate web of economics” that includes multinational interests and laws, private companies who breed animals, supply equipment, provide support services for product development, and more.

Coupled with the European Union, Israeli, and India’s ban on cosmetic testing, the predicted changes for cosmetic testing in 2014 by the China Food & Drug Administration, and the mounting strength of collective animal rights and protection organizations, the international trend toward non-animal testing has progressed too far to be reversed.

“We have our foot in the door and are turning the corner toward eliminating the use of animals in medical research and transitioning to non-animal, human-based research methods that will accelerate science and enhance public safety and health,” Dr. Pippin states. “This is the biggest single change in my decade of involvement.”