Klay Thompson led the Warriors with a career-high 38 points including 5-for-7 shooting from downtown while David Lee added 24 points, eight rebounds and five assists.
Stephen Curry ran into foul trouble early, but finished with 10 points, six assists and four rebounds in 24 minutes.
The Warriors were up 59-40 at the half, but increased the lead to 34 points by the end of the third quarter in which Golden State shot 55 percent from the floor.
Kent Bazemore made it a 35-point lead on a three-pointer in the fourth.
Draymond Green chipped in seven points, seven rebounds, two assists and one steal in 19 minutes off the bench, but in truth everyone contributed to the victory - Mo Speights grabbed seven rebounds while Jermaine O'Neal and Toney Douglas combined for 17 points.
Head coach Mark Jackson played his entire bench and the team chemistry and collective passing were outstanding.
NOTES: Harrison Barnes (foot) and Festus Ezeli (knee) did not play. ... Kobe Bryant (Achilles) did not play for the Lakers. ... The Warriors play the Clippers in Los Angeles on Thursday night at 7:30 p.m. PT.