Originally printed in Portal, Virtue's Ruin is one of 15 terrific Magic: The Gathering cards featured in Wizards of the Coast's From the Vault: Annihilation. This powerful sweeper effect can be absolutely devastating against the right player.
Virtue's Ruin - 2B
Sorcery (Mythic Rare)
Destroy all white creatures.
All must fall, and those who stand highest fall hardest.
Unlike its sibling Perish from Tempest, Virtue's Ruin doesn't have the clause "they can't be regenerated." It's more a counterpart to Nature's Ruin from the same set, however because Perish was actually a tournament legal card at the time whereas cards which were printed only in Portal and Starter expansions were not, many don't know of its existence.
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