Henderson thinks people who need to use steroids are mentally weak, so there's no chance they would make it through 25 minutes of war with him.
"My thing with the whole steroid thing and whatnot -- like I understand part of a competitors nature is to take whatever edge, whatever advantage you can get to be the best," Henderson said. "To that I just say if I'm facing a person - it happened in college wrestling, sadly it shouldn't, but it happened in college wrestling people on steroids and whatnot. But if I know someone is mentally weak enough to take steroids, ‘Oh, I need the extra edge, I need to do this', and they know it's illegal, they know it's wrong and they do it."
Henderson, 29, is scheduled to fight Gilbert Melendez on Apr. 29 in San Jose, Calif., in the main event of UFC on Fox 7.
"If you're so mentally weak that you have to take steroids, me five-rounds in the cage with you, I will destroy you," Henderson said. "Cause you are mentally weak. So I'm all for it, if you want to take drugs go ahead and take drugs I don't really care but I'm going to whoop your butt because you are mentally weak and that's where you win fights in the mental stage. If you're weak enough to break down, I'm going to kill you."
Henderson is coming off a convincing victory over Nate Diaz on the UFC on FOX 5 card in Dec. 2012, while Melendez hasn't lost since 2008. Melendez is coming off a win over Josh Thomson.