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Turnovers will play biggest role for the 49ers vs. Seahawks

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Colin Kaepernick has thrown only eight interceptions this season, but four of them have come against the Seattle Seahawks. For 2013, he has a 21-8 touchdown-to-interception ratio in the regular season.

Ball security will be one of the most important things in the upcoming NFC Championship game. The Seattle Seahawks lead the NFL in turnover margin and Jim Harbaugh took note of how well they can create takeaways. In the regular season, Seattle's defense forced 39 turnovers.

"The Seattle defense is looking to get the ball at all times [by creating] turnovers in any situation. [They] generate them on all downs," Harbaugh said on Wednesday. "They're looking to take the ball away."

Harbaugh has emphasized ball security throughout practice, hoping no one will cough up any possession to the opposition. San Francisco has had three fumbles and four interceptions combined in their last two trips to CenturyLink Field.

Kaepernick threw three interceptions during the 29-3 loss in Week 2 of the 2013 season. The first interception was a form of bad luck, where the ball was tipped by nickel CB Walter Thurmond before it landed in the hands of Earl Thomas. His pass was intended for Vernon Davis while in the end zone.

In two home wins against Seattle from 2012 and 2013, Alex Smith threw an end zone interception to keep Seattle in the game which Brandon Browner was able to grab. In the Week 14 meeting, Colin Kaepernick forced a deep ball to Michael Crabtree which was intercepted by Byron Maxwell.

Kaepernick threw one interception against the Packers, but didn't throw one against the Panthers last week. He was fortunate that a few bad decisions didn't lead to an interception the other way.

The biggest key is to not start an crowd uproar from a turnover early on in the game. Kaepernick expects a fast start without looking back.

"I think we came out and executed better to start games [since Week 2]," Kaepernick said on Wednesday. "That's something we try to do throughout the whole game."

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