On a very simple level, the endocrine system is a collection of (organs) glands that secrete (or produce) chemical messages (better known as hormones). Importantly, the endocrine system maintains homeostasis (balance) and long-term control using chemical signals, and furthermore, it works in parallel with the nervous system to control growth and maturation along with homeostasis.
Significantly, when one of the organs or glands in the endocrine system (i.e. the pancreas) fails to secrete hormones or function in normal ways, it places a great strain on the body. When the pancreas stops producing Insulin, a person gets Type 1 diabetes. Simply put, Type 1 diabetes is an autoimmune disorder where some other part of the body's immune system attacks pancreatic cells, preventing them from producing insulin.
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