And though the Dome may be more than half filled with raging "Cheesehead" Packer fans, the Rams are expected to focus solely on their own goals and priorities, which head coach Jeff Fisher has made very clear are all about getting ready for the regular season opener against the Arizona Cardinals on September 8.
Fans of the Blue & Gold though, are still pretty jacked up about their team playing their first game in the Dome this year -- as the old football adage goes, the preseason games don't count, but they do matter.
And with that in mind, here's a list of five things Rams fans might want to look out for during tonight's preseason matchup against the Packers:
No. 1 -- Tavon Time!
Ever since the days of the Greatest Show on Turf era ended, Rams fans have been clamoring for more speed and excitement out of the offense. And they thought they finally got their wish when the club drafted WR/KR/PR Tavon Austin with the eighth overall pick in last spring's NFL Draft.
But in his debut last week, Austin was only targeted once with a pass once, didn't carry the ball as a runner at all, and only got a couple of opportunities on punt returns.
This week, with the home crowd ready to explode if the rookie makes a big play, look for Fisher and offensive coordinator Brian Schottenheimer to get Austin more chances. What better way to build up some really excitement and hype for the season than to let the new, exciting toy make a couple big plays in front of the home fans?
No. 2 -- O-Line Shuffle
Coming into the season, the Rams felt like their offensive line was one of its most veteran units and that it would be one of the strengths of the team, especially early in the season.
But right tackle Rodger Saffold's dislocated left shoulder has thrown a monkey in the wrench for that plan.
Now St. Louis is scrambling to find a replacement that could be ready, and possibly necessary, to play on September 8, should Saffold not be healthy enough to go.
Third-year veteran Joe Barksdale, who played pretty well when given the opportunity last season, will get another shot tonight as Saffold's replacement, and he will be tested, as he goes up against Green Bay sackmaster Clay Matthews, in what should be a fun matchup to keep an eye on.
Also for the Rams, the battle for the starting spot at left guard is still ongoing.
Last week, Chris Williams started and did a good job.
But tonight, it'll be Shelley Smith's turn to start and show his wares. And the -year man out of --- will need a good showing if he's going to supplant Williams, who so far this summer seems to be ahead in the Rams most interesting preseason starting battle.
No. 3 -- Witherspoon Replacing Jo-Lon
With the recent announcement that Jo-Lonn Dunbar will be suspended for the first four games of the regular season, veteran Will Witherspoon will now have to take over as the Rams' right outside linebacker.
And unfortunately, he's got less than four weeks to get ready. So fans might want to keep an eye on the 32-year old, 12th-year man out of Georgia to see if he's still got the legs to handle LB duties in the NFL.
No. 4 -- Secondary Intrigue
Other than veteran cornerback Cortland Finnegan, the Rams are young all over the secondary.
Both projected starting safeties are young, and all the potential backups at corner and safety are as well.
So it should be interesting to see how well they handle tonight's test, which will be going up against one of the best passsing offenses the league has seen the last few years, led All-Pro QB Aaron Rodgers.
No. 5 -- Helmick's Debut?
Will the hometown kid get a shot? That'll be the question many fans ponder once the fourth quarter hits, as local WR prospect Andrew Helmick, who starred the last two seasons at Division II Lindenwood University and became an early training camp fan favorite, hopes to get a chance to play in his first NFL game tonight.
Helmick set school records for career receptions (153), receiving yards (2,828), and receiving touchdowns (32) at Lindenwood and showed an ability to make tough catches and convert third downs early in training camp.
Then he got hurt, and missed several weeks, before returning to practice this week.
Now, he's hoping to get a chance in a game to show that he can be an NFL receiver, and more importantly, one that can help the Rams win games.
August 17 -- vs. Green Bay ......... 7 p.m.
August 24 -- at Denver ............. 7 p.m.
August 29 -- vs. Baltimore ......... 7 p.m.
September 8 -- vs. Arizona ......... 3:25 p.m.
September 15 -- at Atlanta ......... noon
September 22 -- at Dallas .......... noon
September 26 -- vs San Francisco ... 7:25 p.m.
October 6 -- vs. Jacksonville ...... noon
October 13 -- at Houston ........... noon
October 20 -- at Carolina .......... noon
October 28 -- vs. Seattle .......... 7:30 p.m.
November 3 -- vs. Tennessee ........ noon
November 10 -- at Indianapolis ..... noon
November 24 -- vs. Chicago ......... noon
December 1 -- at San Francisco ..... 3:25 p.m.
December 8 -- at Arizona ........... 3:25 p.m.
December 15 -- vs. New Orleans ..... noon
December 22 -- vs. Tampa Bay ....... noon
December 29 -- at Seattle .......... 3:25 p.m.