The smoking habits of male prisoners were the focus of a year long study in Australia.The study showed medication did not prove to be productive in aiding male prisoners in long-term smoking cessation. The study combined nortriptyline, an antidepressant, with a conventional smoking cessation therapy program.
Nortriptyline has not been approved by the Food and Drug Administration for smoking cessation but it is frequently prescribed for that purpose.
The study included 425 male inmates who were confined to prisons in Australia. All had been smokers for an average of 20 years and admitted to smoking 23+ cigarettes per day. Each participant received 10 weeks of smoking cessation therapy, including nicotine patches and therapy. The smoking habits of the participants was studied at three months, six months, and twelve months. By then end of the study the abstinence rate was approximately 11% per group (Reuters 1/1/2013).