The women come in with eight wins and two program records this season and are hopeful of a solid performance against tougher opposition.
The best chance of a medal for the women lies in the distance medley relay of Nina Herrera, Grace Williamson, Stephanie Wangui and Alyssa Diaz who lead the WAC standings with 11:45:21, a school record they set.
UTSA's other great hope for a women's medal is in Shahira Ehiemua who is currently second in the WAC 60m rankings.
The men coming in looking to carry their run of Southland Championships in to their WAC life, coming off the back of seven straight titles in Southland.
The Roadrunners lead WAC standings in five events the 60m hurdles, distance medley relay, high jump, long jump and triple jump with another six sitting in second place.
Richard Garrett Jr. sits outside of the top two, tenth, in shot put but comes in to the event in good form having won WAC Field Athlete of the Week last week.
UTSA have claimed 14 gold medals already this season and will surely add to that this weekend while also looking to take home another trophy.