Skip to main content
  1. News
  2. Science & Space

Researchers prove longer, healthier life from one protein supplement

See also

Synthetic activation of the gene sirtuin1 produces longer life, healthy aging, and a host of health benefits according a report by Dr. Rafael de Cabo of the National Institute on Aging at the National Institutes of Health published in the journal Cell Reports on Feb. 27, 2014.

The researchers fed one group of mice 100 milligrams per kilogram of body weight of SIRT1720 daily beginning at six months of age. SIRT1720 activates the function of the sirtuin1 gene at extremely accelerated rates. A second group of mice received no supplement in their diet.

The mice that consumed SIRT1720 demonstrated an extended life span of 8.8 percent, lower body fat, a lower body weight, improved muscle function, improved motor coordination, a reduction in total cholesterol levels, a lowering of LDL cholesterol levels, a lower potential to develop diabetes, and a reduction in chronic inflammation compared to the mice that consumed no SIRT1720.

The synthetic initiation of the sirtuin1 gene by SIRT1720 could reduce the rates of heart disease, diabetes, and many age-related diseases in an increasingly older population in the United States.

Dr. de Cabo says "It illustrates that we can develop molecules that ameliorate the burden of metabolic and chronic diseases associated with aging."

The sirtuin1 initiator SIRT1720 is manufactured by Sirtris Pharmaceuticals that is a part of GlaxoSmithKline.

Advertisement

News

  • Baseball Hall of Fame
    The Baseball Hall of Fame in Cooperstown welcomes six new inductees
    Video
    Video
  • 2012 do-over
    If we were to re-do the 2012 election, a new poll suggests Romney would win
    Politics
  • Boko Haram
    Boko Haram kidnaps the wife of the vice prime minister of Cameroon
    World News
  • Ceasefire breaks
    Israel's Benjamin Netanyahu claims Hamas broke another brief ceasefire
    Gaza
  • Close call with CME
    Scientists tell how Earth survived a giant solar flare back in 2012
    Space
  • Comic-Con
    What's going on at Comic-Con? Get all the latest updates here
    Comic-Con

Related Videos:

  • Buzz Aldrin and the American flag on the moon
    <iframe width="420" height="315" src="//www.youtube.com/embed/O4KxesvbiMU?VQ=HD720&amp;allowfullscreen=true&amp;autoplay=1"></iframe>
  • Orbital Sciences rocket brings supplies and experiments to space station
    <div class="video-info" data-id="518318477" data-param-name="playList" data-provider="5min" data-url="http://pshared.5min.com/Scripts/PlayerSeed.js?sid=1304&width=480&height=401&playList=518318477&autoStart=true"></div>
  • Liftoff Apollo 11
    <iframe width="420" height="315" src="//www.youtube.com/embed/zGNryrsT7OI?VQ=HD720&amp;allowfullscreen=true&amp;autoplay=1"></iframe>