This offseason, the pair will wear the patriotic colors for the U.S. national team, representing the country in the second World Baseball Classic.
Perez, a two-time all star as the Indians' closer, will round out a bullpen expected to include San Diego Padres reliever Luke Gregerson.
"I am happy to say that I will be pitching for Team USA in the upcoming 2013 WBC. #Honored #Humbled #Ready," Perez tweeted this past weekend.
Pestano has been a standout reliever for the Tribe bullpen, posting a 2.45 ERA and 3.33 strike out per walk ratio over the past two seasons.
"Just got the second best phone call of my career. I'm going to be wearing the Stars and Stripes in the WBC. #trulyhonored #childhooddream," Pestano also tweeted.
The international baseball tournament first began in 2006 and has since been replayed in 2009. Japan enters this coming tournament as the defending champions, having won both contests.
This coming year's tournament features 16 teams from various countries including Brazil, Canada, Chinese Taipei and others.
The U.S. team will play its first game on March 8 against Mexico at Chase Field in Phoenix, Arizona.
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