The comedic actor has been rumored to be considered as a contender for the superhero role, along with Joseph Gordon-Levitt who has appeared in several comic book adaptations including The Dark Knight Rises (2012) and is rumored to be gearing up for DC Comics Sandman.
Sources tell Variety that Rudd is in early negotiations with the studio.
Edgar Wright (Shaun of the Dead, Scott Pilgrim vs. the World) is set to write and direct the film, with Joe Cornish onboard as co-screenwriter.
An official announcement has not yet been made by Disney nor Marvel.
Rudd, best known for his comedic films such as cult classic Clueless, Knocked Up, and This is 40, recently stars alongside Will Ferrell in Anchorman 2: The Legend Continues out this Friday (Dec. 18).
Ant-Man has a release date of July 31, 2015.