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Oxygen particle foam injects into the blood

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Geobeats posted their video report on injectable oxygen to The Examiner Tuesday, April 8, 2014. The injectable oxygen particle foam was developed at Boston Children's Hospital. It is meant to be injected directly into the blood. The discovery has been previously reported in Nature and Science. You may also link here to the Geek-O-System and the Shots articles cited in the video report. And it was also reported in According to the shots article BCH cardiologist John Kheir thought of the invention upon the death of a little girl suffering from lung hemorrhages.

"That was in 2006." The description of the injectable oxygen particle foam was published in the major scientific journals (listed above) June 27, 2012. The deceased girl could not be connected to a heart-lung machine in time to save her. That led to the ideation challenge of getting oxygen into the patient's bloodstream rapidly. But you can't inject gases (like oxygen) directly into the bloodstream - death is the likely result. Liquid oxygen and other liquids would be impractical, dangerous. Hence the concept of creating a particle that can hold oxygen for rapid transfer to the blood.

The PubMed article describes the particles as self-assembling and composed of lipids and pure oxygen. Of course, the particles in the foamy material are extremely small - greater than 1 micrometer to less than 5 micrometers in size. It was then mixed (not injected) with human blood samples and found to deliver oxygen in less than 5 seconds. Lab rabbits with impeded windpipes received injections of the experimental oxygen particle foam. All but one of them survived after the treatment. The treatment can't be used as a permanent oxygen-fix for patients. It would have to be delivered/received every 15 minutes or so.

This was happening in 2012 - a check of BHC's research and innovation pages has not shown any results for the oxygen particle foam. It was thought that the injectable oxygen material could be used in a number of live-saving instances. Dr. Kheir did give a presentation at Georgetown University (April 19, 2013) regarding intravenous oxygen. It is hoped that the potential life-saving creation is undergoing more development or even clinical trials.


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