Skip to main content
  1. News
  2. Science & Space

New study shows no heart regeneration in mammals

See also

Ditte Andersen of Odense University Hospital and the University of Southern Denmark and colleagues attempted to replicate a reported regeneration of mouse hearts without success according to the researcher’s report in the April 3, 2014, edition of the journal Stem Cell Reports.

A previous study in 2011 supposedly demonstrated that regeneration of the mammalian heart was possible. The researchers in this study removed the lower 10 percent of the heart of neonatal mice that were one day old. The mice regenerated the removed heart muscle. The concept was that an innate but temporary enzymatic or hormonal system could be responsible for the regeneration of hearts in mammals but the capacity was lost after seven days.

Andersen and colleagues replicated the original 2011 study parameters exactly and found no heart regeneration was seen. The mouse hearts that had the apex removed were smaller, weighed less, formed scar tissue, had more fat, and produced no evidence of regeneration.

The goal of regeneration of heart tissue in part or in total is an ambitious goal and necessary because heart disease is the number one cause of death in the world,

Andersen’s work does not dismiss the potential for producing regeneration of heart tissue in mammals. The research does emphasize the need for replication of work that has such profound implications for human health prior to publication.



  • Baseball Hall of Fame
    The Baseball Hall of Fame in Cooperstown welcomes six new inductees
  • 2012 do-over
    If we were to re-do the 2012 election, a new poll suggests Romney would win
  • Boko Haram
    Boko Haram kidnaps the wife of the vice prime minister of Cameroon
    World News
  • Ceasefire breaks
    Israel's Benjamin Netanyahu claims Hamas broke another brief ceasefire
  • Close call with CME
    Scientists tell how Earth survived a giant solar flare back in 2012
  • Comic-Con
    What's going on at Comic-Con? Get all the latest updates here

Related Videos:

  • Buzz Aldrin and the American flag on the moon
    <iframe width="420" height="315" src="//;allowfullscreen=true&amp;autoplay=1"></iframe>
  • Orbital Sciences rocket brings supplies and experiments to space station
    <div class="video-info" data-id="518318477" data-param-name="playList" data-provider="5min" data-url=""></div>
  • Liftoff Apollo 11
    <iframe width="420" height="315" src="//;allowfullscreen=true&amp;autoplay=1"></iframe>