Albuquerque (76-68) finished with a winning record for the fourth time in five seasons as a Los Angeles Dodgers affiliate. The Isotopes have winning marks in seven of 11 seasons and have finished in second place in their division six times.
Dodgers prospect Matt Magill (6-2), who has had an erratic season split between Albuquerque and Los Angeles, was effective enough in his last outing of the year. The right-hander allowed two runs on six hits and just one walk in 5.2 innings. He struck out three batters.
Matt Angle snapped a 1-1 tie with a two-run homer to right field in the third inning, putting the Isotopes ahead for good.
The Zephyrs (72-72) made things interesting as Joe Mahoney's RBI single in the fourth cut the lead to 3-2.
Damaso Espino would tack on a crucial insurance run with a one-out RBI single to make it 4-2 in the ninth.
In the bottom of the frame, Javy Guerra gave up a one-out, solo homer to Kyle Skipworth. After Mahoney popped out, Chris Valaika reached on a throwing error by shortstop Justin Sellers. Guerra then struck out pinch hitter Jordan Brown on a foul tip to end the game and earn his 12th save.
Eliezer Alfonzo led Albuquerque at the plate, going 3-for-4 with an RBI single in the first inning.
Most of the Isotopes will now disperse for the offseason, some playing in winter leagues and others waiting until spring training. A few players still on the 40-man, including Sellers, Guerra, Magill, utility man Elian Herrera and outfielder Alex Castellanos, will hope for a call-up from the Dodgers on Tuesday.
Look for a full recap of the Isotopes' season here on Tuesday and a look ahead to next year on Wednesday.