Mayo Clinic writes that statins are drugs which can lower your cholesterol. These drugs work by blocking a substance which your body needs to make cholesterol. Statins may also assist your body in reabsorbing cholesterol that has built up in plaques on your artery walls. Although many people tolerate statins well, these drugs do have side effects, which should be carefully monitored by a physician. The European Society of Cardiology (ESC) reported on Aug. 31, 2013, High dose statins prevent dementia.
In a study of about 58,000 patients it was found that high potency statins had the strongest protective effects against dementia. According to research presented at the ESC Congress by Dr Tin-Tse Lin from Taiwan, high doses of statins prevent dementia in older people. Dr Lin has said, “Statins are widely used in the older population to reduce the risk of cardiovascular disease. But recent reports of statin-associated cognitive impairment have led the US Food and Drug Administration (FDA) to list statin-induced cognitive changes, especially for the older population, in its safety communications.”
This study found that the adjusted risks for dementia were significantly inversely associated with the increased total or daily equivalent statin dosage. The patients who were given the highest total equivalent doses of statins had a 3-fold decrease in the risk of developing dementia. Similar results were found to exist with the daily equivalent statin dosage. The potency of the statins was found to be a major determinant in reducing dementia. Dr Lin and his associates concluded that high doses of statins, particularly high potency statins, prevent dementia.