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‘Grey’s Anatomy’ spoilers: Will Meredith and Derek split for good in season 11?

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McDreamy could be headed for a McDivorce. Or the dreamy doc could at least be facing some major trouble in paradise. The upcoming 11th season of “Grey’s Anatomy” will pick up with Seattle-based couple Meredith and Derek (Ellen Pompeo, Patrick Dempsey) butting heads over Derek’s decision to take a dream job in Washington, D.C. And now, “Grey’s” show runner Shonda Rhimes has gone on record as saying she’s not ruling out an actual break up for the longtime lovebirds.

On Thursday, TV Line reported that the ambiguous “Grey’s” creator said, “I’m not going to say that Meredith and Derek are never going to break up. I’m not going to say that simply because we’re writing a story and we’re on this long, long journey. I’ve learned never to say absolutes about anything anymore. People always say, ‘Seven seasons ago you said… ‘Well, I didn’t think we’d still be here.”

While Rhimes has long hinted that the couple will live happily ever after (in 2008 she said her goal was to get the couple together “for good”), she did offer up an update to her own personal view of the couple’s rocky romance, which took a recent turn when Mer refused to give up her career so her hubby could take a high profile political job: “I was not interested in telling the story of a really good marriage that breaks up because of this,” she added. “There’s work involved in keeping an amazing marriage amazing, and I would personally like to watch what happens when [they try] to fight through it.”

So, will TV’s favorite power couple fight to save their marriage? Or will they throw in the towel like so many television drama couples have done before them?

Rhimes previously told Entertainment Weekly she thinks the Shepherds can work through this little bump in the road. (Although it’s not that little; Dude was offered a job working for the POTUS. It doesn’t get much McDreamier than that!)

“I don’t think that it’s a marriage-ending argument,” Rhimes told EW. “It feels very TV for people’s marriages to end over easy things or hard things. I actually would like to watch a couple have a hard time in their marriage, and have it not be that that means their marriage is over. There’s something really great about watching a couple have a mature marriage where stuff goes wrong, things are hard, and people try to push through it and figure it out.”

Of course, Rhimes did dish that that Season 11 of the ABC medical drama will pick up with the couple still fighting. Which leads us back to her comment that she can’t actually promise they will never break up. Because, as a smart show runner knows, you can never say never.

The 11th season of Grey’s Anatomy” premieres on Sept. 25 at 8 p.m. on ABC.

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