Florida quarterback Jeff Driskel was hit on a pass that resulted in an interception and score for Tennessee. Grabbing for his ankle, Driskel soon left the field on crutches and was taken to the student health center for X-Rays.
Trailing the Volunteers by 7-3 at the end of the first quarter, things were not looking good for the Gators.
Highlighting how serious the injury to Driskel could be for the Gators' long-term prospects, he was replaced on the field by Tyler Murphy, a redshirt sophomore who had yet to throw a single live pass in a college game.
The Gators scored to make it 10-7 in the second quarter, when a fumble caused a turn-over that gave Tennessee good field position. Almost immediately, the Volunteers gave the ball back with a sloppy interception that resulted in another scoring drive for the home team.
When asked if Jeff Driskel might return in the second half, Gators coach Will Muschamp replied: "Well, he's out for the game, definitely. I don't know how much past that, but this is Tyler's game."
Muschamp later revealed that he was told at half-time Driskel will miss the remainder of the season and may need surgery on his ankle.
In the second half, Murphy stepped up and lead his the team down the field to 21 points during the second half. Tennessee switched out quarterbacks, but failed to recapture their early momentum.
"I've got all the confidence in the world in Tyler, we've always had that," said head coach Will Muschamp during a post-game interview on CBS. "Creating some plays with his legs and his arm, he directed our offense in an outstanding manner. He's the reason why we won the football game today."
Both teams have gotten their seasons off to rocky starts this year and were looking for a win to get things back on track. The Volunteers suffered their worst loss in over 100 years last week on the road against the second-ranked Oregon Ducks.
Florida heads to Kentucky next week, while Tennessee will play host to the South Alabama Jaguars.