Hopefuls looked to improve their draft stock while increasing their chances of signing as an undrafted free agent.
And though it doesn't feature the household names of other college all-star games, the squads are led by ex-NFL head coaches Dick Vermiel and Dennis Green and several players have gone on to stick with NFL teams including the 49ers.
Current 49ers' guard Ryan Seymour, nose tackle Mike Purcell (practice squad) and fullback Alex Debniak (injured reserve) played in last years contest.
According to the live broadcast on NFL Network, eight players were drafted in 2013 and 11 made NFL rosters.
This off-season the 49ers are likely to have 13 picks (including compensatory picks) again while a host of other players will get shots as undrafted free agents.
Here are five players from the Collegiate Bowl who could wind up with San Francisco.