"Late to the party, but happy to be here!" she tweeted. "140 characters should keep me from rambling . . . someone told me it doesn't all have to fit in 1 tweet."
As of Tuesday evening, Barrymore had 11,723 followers.
She was following only one account, @flowerbeauty, her own cosmetics brand.
Barrymore, 38, won the Young Artist Award for Best Young Supporting Actress in a Motion Picture in 1982 at the age of seven for her portrayal of Gertie in “E.T. the Extra-Terrestrial.”
Other notable childhood roles include “Firestarter, "Irreconcilable Differences," "Cat's Eye" and the TV movie "Babes in Toyland."
As an adult, she has been nominated for and/or earned awards for "Scream," "The Wedding Singer," "Ever After," "Never Been Kissed," "Charlie'Angels," "50 First Dates," "Fever Pitch" and "Grey Gardens."
She has had a recurring role as the voice of Jillian Russell in "The Simpsons."
She is shooting a film titled “The Familymoon” with Adam Sandler, according to IMDb.com.
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