As Guerrero's throw hit the ground across home plate, Baylor grabbed the ball and collapsed.
Baylor was helped up by Guerrero, and helped off the field by the Angels training staff. Baylor was sent to UCI Medical Center for test, where it was determined that he suffered a broken femur.
"Our thoughts and prayers are with Don right now," Angels manager Mike Scioscia said. "Obviously it's a freak injury."
Angels outfielder Mike Trout expressed his thoughts on Baylor's injury.
It got me sick when I was warming up seeing that and then hearing what happened in the dugout. I just hope and wish for the best."
The 64 year old Baylor overcame a battle with multiple myeloma, a cancer that attacks bone marrow and plasma. He was first diagnosed back in 2003, where the average survival rate is approximately five years. Baylor's extensive resume included managing the Rockies and Cubs, before joining the Angels staff this of season after leaving the Arizona Diamondbacks.
Baylor is well respected in the clubhouse amongst the staff and players.
"He's a big part of our team and he has a lot of respect from the guys here," said Howie Kendrick. "We definitely enjoy working with him in the cage."
Baylor undergoes surgery on Tuesday, and will take approximately 4-6 months to recover from the injury.
Guerrero and Baylor are the Angels to win American League MVP's.
Dave Hensen who was also hired in the off season, will assume responsibilities while Baylor is away recovering.