Despite Lovelocke's performance, the winning score came from Courtney Brown's 41-yard burst late in the fourth quarter to put the Panthers (3-2) up 56-41 over the Lumberjacks (2-3).
Lovelocke had touchdown passes of 13, 3, 6 and 39 yards. He also ran the ball in from the four-yard line twice and also the three-yard line of SFA.
Lovelocke's effort was necessary because of Prairie View's porous secondary. Two weeks ago against Southern, the Panthers allowed the Jaguars to come back from a huge deficit to win 62-59 in double overtime.
This time around, Stephen F. Austin's signal caller Brady Attaway burned Prairie View's secondary for 662 yards and four touchdowns. Two of the scores were for 80 yards and 76 yards.
Gus Johnson did the same to PV's defensive front line, rushing 18 times for 179 yards and a score.
Leading 35-31 at the half, Lovelocke opened the third quarter with a long drive culminating in his three-yard touchdown run.
He added a four-yard run for his third rushing TD of the game to put PVAMU up 49-34 heading into the final period.
That's when Attaway connected with Aaron Thomas, who cut through defenders for 76 yards to cut the deficit to 49-41.
Brown's 41-yard scoring run gave Prairie View breathing room to endure Attaway's 26-yard scoring pass to Mike Brooks with 1:43 left to play.
The game went the Lumberjacks' way early on.
Gus Johnson and Joshawa West each scored on one-yard runs to give SFA a 14-0 lead.
Prairie View answered with Lovelocke's 13-yard toss to Gabe Dunlap and, moments later, a 3-yard TD pass to Patrick Gant.
Lovelocke then ran in his first touchdown, from four yards out, to put Prairie View up 21-14 to end the first quarter.
Lovelocke found Deandre Cooper for a 39-yard touchdown and PV went up 28-14.
Stephen F. Austin got the next three scores, however, beginning with Attaway's seven yard pass to Marquis Mosley.
After Jordan Wiggs kicked a 28-yard field goal, Attaway hooked up with D.J. Ward for an 80-yard pass play to the Lumberjacks retook the lead, 31-28.
Lovelocke then found Gant again, this time from six yards out, to give Prairie View its 35-31 halftime lead.
The game featured five 100-yard receivers.
Thomas led SFA and all receivers with 242 yards on 10 catches. Ward finished with 170 yards on eight catches and Tyler Boyd had 10 catches for 100 yards.
Cooper paced Prairie View with 113 yards on four catches, while Dunlap finished with 100 yards on 10 haul-ins.
Jackson State 19, Southern 14
Clayton Moore scored from two yards out to give the Tigers the lead for good against the Jaguars in a SWAC matchup at Mumford Stadium in Baton Rouge.
Jackson State (3-2) trailed 7-3 after Southern's Lenard Tillery burst out of the crowd for a 60-yard touchdown run in the first half of the low-scoring affair.
Ryan Deising's 39-yard field goal cut it to 7-6 to start the second half.
When Southern tried to answer, Javancy Jones sacked quarterback Dray Joseph and forced him to fumble into the hands of Cedric Morgan at the Southern 9.
Moore's TD run put Jackson State up, 13-7, a few plays later.
Rakeem Sims added his own two-yard scoring run to give Jackson State a 19-7 edge.
Joseph connected with Lee Doss from nine yards out near the end of the third quarter to cut the deficit to 19-14, but neither team managed anything in the fourth quarter.