Crohn’s disease is a type of autoimmune disorder that involves primary T cells. Like many other autoimmune disorders, the exact cause of Crohn’s disease remains unknown.
Crohn’s disease is often called inflammatory bowel disease because the immune system targets cells in the gastrointestinal tract, which often leads to inflammation of the bowels. Although Crohn’s disease can occur anywhere in the gastrointestinal tract (between the mouth and the anus), it most commonly effects the ileum, a small segment of the small intestine.
Many scientists have hypothesized that Crohn’s disease is often the result of a combination of things, such as an inherited, mutated immune system gene, a trigger for the gene to become active, or exposure to intestinal bacteria, which may all contribute to inflammation of the bowels.