Of course, Punk's decision to leave the WWE could be part of a scripted storyline.
However, the situation seemed very real to wrestling fans after Punk took to Twitter to tweet what appeared to be a farewell message to WWE Universe.
"Thanks for all the support. Keep being you guys, it's pretty cool," Punk tweeted on Jan. 27.
As reports would have it, CM Punk told WWE head honcho Vince McMahon he was "going home" to Chicago, after he wasn't scripted to appear on Monday night's episode of Monday Night Raw.
Punk did not appear on the Monday Night Raw show in Cleveland, Ohio, and he also was not at the WWE Smackdown event filmed last night.
CM Punk's WWE contract is expiring in less than a year, so many WWE fans believe he has left the company for good.
If Punk leaves pro wrestling, he might be heading to the UFC.
Earlier this month in an interview with MMA Fighting reporter Ariel Helwani, Punk hinted that he might want to test his skills in an MMA competition.
"I think if I talk to Dana [White] about it, it becomes that much more real," Punk said of a possible fight in the UFC. "Plus if you're Dana, what do you do with a guy like CM Punk who comes to him and says that?"
Punk also said he would be open to competing on the UFC's "TUF" reality show, to see if he has what it takes to fight in MMA.
"Sure," Punk said when asked if he would do the show. "That's the interesting thing. Not tooting my own horn and saying I'm a megastar or anything, but do you put CM Punk on [The Ultimate Fighter]?
"See that's the thing. We're talking about it. I don't know."
Punk saw what happened when Brock Lesnar came over to the UFC. He sold tons of pay-per-views and put plenty of fans in the seats.
The Chicago native knows he could have a similar effect on UFC ratings if he tried an MMA fight.
"I have this notoriety and I have this presence, so do you put that on a small show or do you start off in the UFC? Maybe I just get guzzled. Who knows? But think of all the people who want to see me get my ass kicked!" Punk exclaimed. "Think about that. So it's a really interesting question I think.
"It's like what do you do with that? Do you put me in a UFC Octagon and does that do a good buyrate because people are interested in seeing it, or do people just want to see me get beat up? And either way everyone makes a bunch of money. I get punched in the face four nights a week, and I'm not saying it's any easier or any harder than what I do. There's similarities and there's differences."
Is Punk truly finished with the WWE?
Time will tell how it all plays out, but pro wrestling fans have seen wrestlers leave and come back plenty of times in the past. In all likelihood, WWE Universe hasn't seen the last of CM Punk.
He might genuinely be unhappy with how he has been treated lately, but there's a good chance he'll come back someday down the road.