Skip to main content
  1. Life
  2. Health & Fitness
  3. Weight Loss & Dieting

Causes of depression

Everyone gets sad from time to time. However when sadness becomes more intense and lingers for extended periods of time, it eventually turns into depression. Depression can be detrimental to one’s physical as well as mental health.

There are many causes of depression, including biological changes such as a shortage in the number of neurotransmitters, or chemicals inside the brain. Other causes could be heredity, hormone changes, lack of social activity, chronic health conditions, physical as well as mental trauma, drugs, alcohol, and even events such as the 911 attacks in 2001. Even positive events in one’s time can cause stress that leads to depression, such as major changes in job or marital status, new home in a new location, major purchases, and other major changes in the course of one’s daily life.

Depression is a condition that occurs through no fault of the individual, nor does it occur through character flaw. Anyone can become depressed at any time. For treatment and advice for depression in the Knoxville, TN area, please see the following resources.




Knoxville Health and Medical Directory




  • Johnny Manziel
    Should Johnny Manziel apologize for his hard partying over the offseason?
    Today's Buzz
  • Crop circles
    Similar crop circles appeared in Germany and England within days of each other
    19 Photos
  • Advanced placement
    The AP program is gaining traction as a key component in college admissions
    5 Photos
  • Beach hats
    Beat the heat with the best summer beach hats for women
    Beach Hats
  • Expectations for ministry
    Pastor preaches to newly ordained ministers about expectations for ministry
    6 Photos
  • Medical symptoms
    See which symptoms should cause you to seek a doctor’s attention right away
    6 Photos