The Reds (74-59) not only missed a chance to catch St. Louis (78-54), but also Pittsburgh (76-55) who has now lost three straight after losing 7-6 to Milwaukee.
Latos (13-5) started off bumpy allowing three straight hits to open the game capped by an RBI single by Matt Holliday. Allen Craig bounced into a double play to allow another run to score and give St. Louis a quick 2-0 lead.
The only mark against Cardinals starter Joe Kelly (6-3) was a solo blast by Shin-Soo Choo, his 100th career homer, to make it 2-1 in the fifth inning. Cincinnati would fail to get another base runner on after the fifth as they were retired in order by four different Cardinals pitchers: Kelly, Kevin Siegrist, Trevor Rosenthal, and Seth Maness.
St. Louis put together an insurance run in the sixth and seventh inning against Latos and then two more in the eighth against Alfredo Simon.
The Reds will look to salvage one game in St. Louis, but will have to do so against Cardinals ace Adam Wainwright (15-7). He is 1-1 in two nearly identical outings against the Reds tossing seven innings and allowing two runs in both starts. Homer Bailey (8-10) counters hoping to make it four straight decisions with a victory. Bailey has not faced the Cardinals since the first month of the season lasting just 10.1 innings in two starts (0-2) while allowing 11 runs on 18 hits.