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Cannabinoids are a group of terpenophenolic compounds present in Cannabis (Cannabis sativa L). Currently, 538 natural compounds were identifed from this plant. 43 of these 108 are identifed as cannabinoids, which are C21 compounds uniquely present in Cannabis sativa L. There are ten main types of cannabinoids and fourteen different cannabinoid subtypes. Tetrahydrocannabinol (THC) is the principal psychoactive ingredient in cannabis, but it also has other effects. Cannabidiol (CBD) and cannabinol (CBN) are the other two most prevalent natural cannabinoids and have received the most study. All three are listed as ingredients in Sativex®, the only multi-cannabinoid medicine currently approved for marketing (only in Canada.)
Cannabinoids were first discovered in the 1940s, when CBD and CBN were identified. THC was not identified until 1964, but by that time cannabis had been removed from the pharmacopeiae of most countries, making further research on the plant difficult.
There are three general types of cannabinoids:
1 Phytocannabinoids occur uniquely in the cannabis plant.
2 Endogenous cannabinoids are produced in the bodies of humans and other animals.
3 Synthetic cannabinoids are similar compounds produced in a laboratory. Forms of synthetic THC are available by prescription in a number of countries, including the US. In the US, synthetic THC is marketed as Marinol®.
For more information check out the Cannabis Science Inc Website
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Very interesting and informative. For anyone interested in the history of why marijuana is illegal, and the damage caused to countless lives by marijuana prohibition there is a very interesting article you should read that I also found on Examiner.
www.examiner.com/examiner/x-20909-Columbia-Independent-Examiner~y2009m8d26-Marijuana-Should-it-be-legalized--Part-I
While I think marijuana and its cannabinoids should be legal I was pleased to find other cannabinoids which worked just as well or better, but because of their molecular structure are still legal even with analog laws. Check out:
www.herbavigor.com/html/cannibinoids.html
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