Can a 20-year-old woman in a toddler's body help solve the mysteries of aging?

Tiny Brooke Greenberg and her Maryland family appeared on Katie Couric yesterday when her program focused on unbelievable medical mysteries. Greenberg is both a 20-year-old woman and a toddler who has not aged since she was four years old.

Brooke Greenberg was born one month prematurely on January 8, 1993 at Sinai Hospital in Baltimore, Maryland. Until she was four, she grew and changed almost like a normal child, but she suffered numerous unexplained medical emergencies. Then between age four and five, she stopped growing. She has remained a 16-pound child since then who is fed through a feeding tube.

“From age one to four, Brooke changed. She got a little bit bigger,” her father, Howard Greenberg told the Katie Couric audience. “But age four, four to five, she stopped.”

The 20-inch little girl still has her baby teeth, wears diapers, travels in a stroller and communicates like an infant would, "like 6 months,” her mother explained on the TV show. “If she’s happy, she’ll giggle and laugh.”

Also appearing on the show was Eric Schadt from Mount Sinai. Schadt has been studying every letter of Brooke's genome to try to figuring out the source of her disorder as well as learn more about the aging process. If it is possible for Brooke to stop aging, perhaps doctors can discover what stops the aging process in her DNA.

However, it appears parts of little Greenburg's body are aging at different rates, and the genes associated with the premature aging diseases are normal, further compounding the mystery.

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Kathryn Darden has worked in the skin care industry for many years at Avon, the Macy's cosmetics department and today an independent Rodan + Fields Dermatologists consultant. You can find Darden at SkinHealthBeauty.com, on Twitter and via email.

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