Writer, actor and producer Harold Ramis, widely known for his role as Egon Spengler in the movie "Ghostbusters", died early Monday morning. The Chicago Tribune reported on February 24, 2014, that Ramis died from complications of autoimmune vasculitis. He was 69.
Harold Ramis began having serious complications with vascultis in 2010. One of the complications left Ramis unable to walk. Vice president of development at Ramis' production company Ocean Pictures, Laurel Ward said Ramis did learn to walk again, but suffered a relapse in 2011. Ward also called Ramis "the world's best mentor".
Harold Ramis starred in and created some of the most successful and memorable comedy films, including "Ghostbusters", "Groundhog Day", "Stripes", "Caddyshack" and "Analyze That".
Celebrities have taken to Twitter to send condolences to Ramis' family and pay tribute to him.
Dan Aykroyd @dan_aykroyd -Deeply saddened to hear of the passing of my brilliant, gifted, funny friend, co-writer/performer and teacher Harold Ramis.
Ron Howard @RealRonHoward - Harold Ramis RIP. no onecould ever top him in terms of somehow being Cool and off-the-charts creative and incredibly kind and gracious.
Steve Carel @SteveCarell - Harold Ramis. Funny, gracious, kind hearted. A joy to have known you.
Billy Crystal @BillyCrystal - Sad to hear my friend Harold Ramis passed away. A brilliant, funny, actor and director. A wonderful husband and dad. Big loss to us all. bc
Actor and comedian Bill Murray, worked with Harold Ramis on several projects in the 80s and 90s and issued the following statement through his lawyer to TIME on the passing of his friend.
"Harold Ramis and I together did National Lampoon Show off Broadway, Meatballs, Stripes, Caddyshack, Ghostbusters and Groundhog Day. He earned his keep on this planet. God Bless him."
Ramis is survived by his wife, two son and a daughter.